Neuroprotective Role of Microbial Biotransformed Metabolites of Sinapic Acid on Repetitive Traumatic Brain Injury in Rats
نویسندگان
چکیده
Sinapic acid biotransformation was studied and screened using eleven fungal cultures. Penicillium chermesinum AUMC 275, Aspergillus ochraceus 11328, Paecilomyces variotii 5618 showed positive results in the production of metabolites. resulted gallic after 10 days incubation with P. chermesinum, protocatechuic 7 A. ochraceus, ferulic 5 variotii. The investigated compounds' a
منابع مشابه
Neuroprotective Effects of Berberine After Severe Traumatic Brain Injury in Male Rats: The Role of IL-1β and IL 10
Background and purpose: Traumatic brain injury (TBI) is the leading cause of death in young people. Berberine is a flavonoid rich in barberries and many traditional Iranian herbal remedies that could be used in treatment of neurodegenerative diseases. These properties make it a viable treatment for neurodegenerative diseases. Therefore, this study intended to investigate the neuroprotective ac...
متن کاملP12: Progesterone Act as Neuroprotective in Traumatic Brain Injury
لطفاً به چکیده انگلیسی مراجعه شود.
متن کاملNeuroprotective effects of gallic acid in a rat model of traumatic brain injury: behavioral, electrophysiological and molecular studies
Objective(s): Traumatic brain injury (TBI) is one of the main causes of intellectual and cognitive disabilities. Clinically, it is essential to limit the development of cognitive impairment after TBI. In the present study, the neuroprotective effects of gallic acid (GA) on neurological score, memory, long-term potentiation (LTP) from hippocampal dentate gyrus (hDG), brain lipid peroxidation an...
متن کاملThe Effects of Cyclooxygenase Inhibitors on the Brain Inflammatory Response Following Traumatic Brain Injury in Rats
Objective(s) Cytokines such as IL-1β are involved in inflammatory responses. This study evaluated the role of two different kinds of drugs (ibuprofen and celecoxib) on brain IL-10 and IL-1β after traumatic brain injury (TBI) in male rats. Materials and Methods Rats were assigned into 6 groups: intact, sham, TBI, and treated rats with vehicle, celecoxib or iboprophen. Cytokine concentrations ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Pharmacophore
سال: 2022
ISSN: ['2229-5402']
DOI: https://doi.org/10.51847/1rj6v3egdu